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Enterosorption as a method of prolonging the life of old animals
FROLKIS, V V | NIKOLAEV, V G | BOGATSKAIA, L N | STUPINA, A S | KOVTUN, A I | SHCHERBITSKAIA, E V | PARAMONOVA, G I | SOBKO, V E | SHAPOSHNIKOV, V M | RUSHKEVICH, I U E
Fiziologicheskii Zhurnal (Kiev). Vol. 30, pp. 30-39. Jan.-Feb.
1984
Experiments carried out on 28-month-old Wistar rats determine the
effect of repeated regimes of enterosorption on the mean and
maximum life span and on certain functional and metabolic
indicators. At certain regimes, there is an increase in the mean
and maximum life span. In the experimental group, the changes that
occur with age in the structure and ultrastructure of the liver,
kidneys, myocardium, intestine, and pancreas are less pronounced
than in the control group. Enterosorption acts to reduce the
duration of pentobarbitol-induced sleep and to lower the quantity
of cholesterol and triglycerides in the blood, triglycerides in
the heart and brain, and cholesterol and triglycerides in the
liver. Enterosorption also increases the biosynthesis of
ribonucleic acid and protein in the liver, kidneys, and adrenal
glands of old animals.
 Descriptors: AGING (BIOLOGY) | GERONTOLOGY | INTESTINES | LIFE SPAN | PHYSIOCHEMISTRY | SORPTION | BLOOD PLASMA | CLINICAL MEDICINE | CYTOLOGY | LIPID METABOLISM | PHYSIOLOGICAL EFFECTS | PROTEIN
METABOLISM | RATS | TOXICITY
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