ProQuest

Deep Indexing added to selected databases

The Melting World of Penguins

 
About CSA Products Support & Training News and Events Discovery Guides Contact Us
Quick Links
> Field Codes
> Serials Source List
> Thesaurus
 
 

Bacteriology Abstracts (Microbiology B)

 
 
The well-rounded, medically-oriented coverage in Bacteriology makes it possible for researchers and clinicians to keep up with the constant changes in this explosive field. With topics ranging from bacterial immunology and vaccinations to diseases of man and animals, the journal provides access to far-reaching clinical findings as well as all aspects of pure bacteriology, biochemistry, and genetics. General microbiologists and bacteriologists aren't the only specialists who turn to Bacteriology each month for important perspectives in the field. The journal is also valuable to environmentalists, medical and veterinary laboratory staff, agricultural researchers, cell biologists, geneticists, toxicologists, and many others.

Subject Coverage
    Major areas of coverage include:
    • Aggressins and toxins
    • Animal bacteriology
    • Antibacterial agents
    • Antibiosis
    • Antibiotics
    • Cell structure and function
    • Culture
    • Ecology and distribution
    • Genetics and evolution
    • Human bacteriology
    • Identification
    • Immunology
    • Invetebrate bacteriology
    • Methodology
    • Microbial symbiosis
    • Plasmids
    • Predation
    • Taxonomy
    • Typing
Dates of Coverage
    1982 - current
Update Frequency
    Monthly, with approximately 1,400 new records added
Size
    Over 0 records as of May 2013
Print Equivalent
    Microbiology Abstracts Section B: Bacteriology
Supplier
    Proquest
    789 E. Eisenhower Parkway
    P.O. Box 1346
    Ann Arbor, MI 48106-1346
    Tel: +1-734-761-4700
Sample Record

    TI:

    Title
    Genetic Diversity of the Q Fever Agent, Coxiella burnetii, Assessed by Microarray-Based Whole-Genome Comparisons

    AU:

    Author
    Beare, Paul A; Samuel, James E; Howe, Dale; Virtaneva, Kimmo; Porcella, Stephen F; Heinzen, Robert A

    AF:

    Author Affiliation
    Coxiella Pathogenesis Section, Laboratory of Intracellular Parasites. Laboratory of Persistent Viral Diseases. Genomics Core Facility, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840. Department of Medical Microbiology and Immunology, Texas A&M University System, Health Science Center, College Station, Texas 77843

    SO:

    Source
    Journal of Bacteriology [J. Bacteriol.]. Vol. 188, no. 7, pp. 2309-2324. 1 Apr 2006.

    IS:

    ISSN
    0021-9193

    EI:

    Electronic ISSN

    1098-5530

    DE:

    Descriptors
    Lipopolysaccharides; genomics; Genetic diversity; Genetic relationship; Open reading frames; Q fever; Gene polymorphism; Genetic structure; Gene deletion; Point mutation; Gram-negative bacteria; Coxiella burnetii

    AB:

    Abstract
    Coxiella burnetii, a gram-negative obligate intracellular bacterium, causes human Q fever and is considered a potential agent of bioterrorism. Distinct genomic groups of C. burnetii are revealed by restriction fragment-length polymorphisms (RFLP). Here we comprehensively define the genetic diversity of C. burnetii by hybridizing the genomes of 20 RFLP-grouped and four ungrouped isolates from disparate sources to a high-density custom Affymetrix GeneChip containing all open reading frames (ORFs) of the Nine Mile phase I (NMI) reference isolate. We confirmed the relatedness of RFLP-grouped isolates and showed that two ungrouped isolates represent distinct genomic groups. Isolates contained up to 20 genomic polymorphisms consisting of 1 to 18 ORFs each. These were mostly complete ORF deletions, although partial deletions, point mutations, and insertions were also identified. A total of 139 chromosomal and plasmid ORFs were polymorphic among all C. burnetii isolates, representing ca. 7% of the NMI coding capacity. Approximately 67% of all deleted ORFs were hypothetical, while 9% were annotated in NMI as nonfunctional (e.g., frameshifted). The remaining deleted ORFs were associated with diverse cellular functions. The only deletions associated with isogenic NMI variants of attenuated virulence were previously described large deletions containing genes involved in lipopolysaccharide (LPS) biosynthesis, suggesting that these polymorphisms alone are responsible for the lower virulence of these variants. Interestingly, a variant of the Australia QD isolate producing truncated LPS had no detectable deletions, indicating LPS truncation can occur via small genetic changes. Our results provide new insight into the genetic diversity and virulence potential of Coxiella species.

    LA:

    Language
    English

    SL:

    Summary Language
    English

    PY:

    Publication Year
    2006

    PD:

    Publication Date
    200604

    PT:

    Publication Type
    Journal Article

    PB:

    Publisher
    American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, http://www.asm.org/

    CL:

    Classification
    J 02740 Genetics and evolution; G 07320 Bacterial genetics

    UD:

    Update
    200605

    SF:

    Subfile
    Genetics Abstracts; Microbiology Abstracts B: Bacteriology

    AN:

    Accession Number
    6747341

    PG:

    Journal Pages
    2309-2324

    JV:

    Journal Volume
    188

    JI:

    Journal Issue
    7

Field Codes
    The following field codes are found in the records of this database. Here they are listed in alphabetical order by two-letter code. See Field Codes and Search Examples for detailed descriptions and search examples.

    AB = Abstract IS = ISSN
    AF = Author Affiliation LA = Language
    AN = Accession Number NT = Notes
    AU = Author NU = Other Numbers
    CA = Corporate Author OT = Original Title
    CF = Conference PB = Publisher
    CL = Classification Code PT = Publication Type
    DE = Descriptors PY = Publication Year
    ED = Editor SF = Subfile Name
    EM = Entry Month SL = Summary Language
    ER = Environmental Regime SO = Source
    IB = ISBN TI = Title
    ID = Identifiers TR = ASFA Input Center Number