Saito, Y; Tanemura, I; Ueda, H; Sato, T

Chemical & Pharmaceutical Bulletin [Chem. Pharm. Bull. (Tokyo)], vol. 46, no. 7, pp. 1777-1179, Jul 1998

The simultaneous determination of the stability constants for the inclusion of fragrance materials with 2-hydroxypropyl- beta -cyclodextrin (2HP- beta -CyD) was investigated in a mixed fragrance materials system using static head-space gas chromatography (SHSGC). The 1:1 stability constants obtained by this method are in reasonable agreement with the corresponding values in the literature. The time required for determination of the stability constant is markedly reduced by this method.